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December/January 2016/2017 (vol. 13/4)

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Research Plus

Impact of atopic dermatitis on skin absorption

People with atopic dermatitis (with or without lesions) experience at least twice the absorption of chemicals through their skin, compared with healthy controls, this systematic review found. It included 40 studies, assessing dermal absorption of drugs (such as topical corticosteroids), dyes and chemicals found in personal care products, cosmetics and cleaning agents. The findings have implications both for the correct dosing of topical treatments for skin complaints and for risk assessments associated with environmental and occupational exposure to chemicals, for example in hairdressing, metalworking and healthcare.

British Journal of Dermatology 2016; online first: doi: 10.1111/bjd.15065.

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Occupational Health at Work December/January 2016/2017 (vol. 13/4) pp40