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February/March 2012 (vol. 08/5)
Aspirin: no impact on cancer mortality
A meta-analysis of nine randomised placebo-controlled trials on low-dose aspirin to reduce cardiovascular disease (CVD) risk finds no significant reduction in cancer mortality or cardiovascular deaths in people without prior CVD1. Non-fatal myocardial infarction risk is reduced, but bleeding risk is significantly increased. Previous research found that aspirin prophylaxis reduced cancer deaths by 20% overall2, leading to suggestions that anyone aged over 45 should take low-dose aspirin routinely.
Occupational Health at Work February/March 2012 (vol. 08/5) pp40